I recently acquired a Wacom Draw tablet, and it was a headache the GUI configurations (buttons, sliders, menu, etc) if pen tip is very sensitive, because you tend to make accidental mistakes very frequently. So I found Threshold parameter in linux wacom driver to set the sensitivity in GUI, and it works perfectly with MyPaint. The problem is that in all other programs (GIMP, Krita, Blender) Threshold parameter has influence in Canvas/viewport, which is a problem. MyPaint is the only one that does not take into account Threshold parameter within canvas, which I consider the correct behavior.
Well, all this is related to this GIMP report I created:
Maybe MyPaint developers can contribute something in that report about how MyPaint manages to do it.